• Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Karavasiloglou, Nena; Hüsing, Anika; Masala, Giovanna; van Gils, Carla H.; Fortner, Renée Turzanski; Chang-Claude, Jenny; Huybrechts, Inge; Weiderpass, Elisabete; Gunter, Marc; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Tjønneland, Anne; Kyrø, Cecilie; Dahm, Christina C.; Vistisen, Helene Tilma; Bakker, Marije F.; Sánchez, María-José; Chirlaque López, María Dolores; Santiuste, Carmen; Ardanaz, Eva; Menéndez, Virginia; Agudo, Antonio; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Butt, Salma Tunå; Borgquist, Signe; Skeie, Guri; Schulze, Matthias; Key, Timothy; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Ellingjord-Dale, Merete; Riboli, Elio; Kaaks, Rudolf; Dossus, Laure; Rohrmann, Sabine; Kühn, Tilman (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
      <i>Background</i> - Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, ...
    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F.; Overvad, Kim; Clavel-Chapelon, Françoise; Fournier, Agnes; Fagherazzi, Guy; Rohrmann, Sabine; Teucher, Birgit; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Quiros, Jose R; Buckland, Genevieve; Sanchez, Maria-José; Amiano, Pilar; Chirlaque, María Dolores; Ardanaz, Eva; Sund, Malin; Lenner, Per; Bueno-de-Mesquita, Bas; van Gils, Carla H.; Peeters, Petra H.M.; Krum-Hansen, Sanda; Gram, Inger Torhild; Lund, Eiliv; Khaw, Kay-Tee; Wareham, Nick; Allen, Naomi E.; Key, Timothy J.; Romieu, Isabelle; Rinaldi, Sabina; Siddiq, Afshan; Cox, David; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-14)
      Introduction: Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with hormonereceptor negative malignancies, and possible interactions by hormone replacement therapy (HRT) use. Methods: Within the European EPIC cohort, Cox proportional hazards models were used ...
    • Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort 

      Botteri, Edoardo; Ferrari, Pietro; Roswall, Nina; Tjønneland, Anne; Hjartåker, Anette; Huerta, José María; Fortner, Renée Turzanski; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Pala, Valeria; Pérez-Cornago, Aurora; Sonestedt, Emily; Liedberg, Fredrik; Overvad, Kim; Sánchez, María-José; Gram, Inger Torhild; Stepien, Magdalena; Trijsburg, Laura; Ljungberg, Börje; Johansson, Mikael B.; Kühn, Tilman; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-31)
      Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35-70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 ...
    • Alcohol intake and breast cancer in the European prospective investigation into cancer and nutrition 

      Romieu, Isabelle; Scoccianti, Chiara; Chajès, Véronique; De Batlle, Jordi; Biessy, Carine; Dossus, Laure; Baglietto, Laura; Clavel-Chapelon, Françoise; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Lukanova, Annekatrin; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; García, José Ramón Quirós; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano, Pilar; Borgquist, Signe; Wirfält, Elisabet; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Ferrari, Pietro; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-09)
      Alcohol intake has been associated to breast cancer in pre and postmenopausal women; however results are inconclusive regarding tumor hormonal receptor status, and potential modifying factors like age at start drinking. Therefore, we investigated the relation between alcohol intake and the risk of breast cancer using prospective observational data from the European Prospective Investigation into ...
    • Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors 

      Robinson, Natassia; Casement, John; Gunter, Marc J.; Huybrechts, Inge; Agudo, Antonio; Barranco, Miguel Rodríguez; Eichelmann, Fabian; Johnson, Theron; Kaaks, Rudolf; Pala, Valeria; Panico, Salvatore; Sandanger, Torkjel M; Schultze, Matthias B.; Travis, Ruth C.; Tumino, Rosario; Vineis, Paolo; Weiderpass, Elisabete; Skinner, Roderick; Sharp, Linda; McKay, Jill A; Strathdee, Gordon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-30)
      BACKGROUND: Childhood cancer survivors (CCS) exhibit significantly increased chronic diseases and premature death. Abnormalities in DNA methylation are associated with development of chronic diseases and reduced life expectancy. We investigated the hypothesis that anti-cancer treatments are associated with long-term DNA methylation changes that could be key drivers of adverse late health ...
    • Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts 

      Wu, Wendy Yi-Ying; Haider, Zahra; Feng, Xiaoshuang; Heath, Alicia K.; Tjønneland, Anne; Agudo, Antonio; Masala, Giovanna; Robbins, Hilary A.; Huerta, María-José; Guevara, Marcela; Schulze, Matthias B.; Rodriguez-Barranco, Miguel; Vineis, Paolo; Tumino, Rosario; Kaaks, Rudolf; Fortner, Renée T.; Sieri, Sabina; Panico, Salvatore; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Braaten, Tonje; Johansson, Mattias; Melin, Beatrice; Johansson, Mikael (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)
      The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung ...
    • The association between body fatness and mortality among breast cancer survivors: results from a prospective cohort study 

      Bonet, Catalina; Crous-Bou, Marta; Tsilidis, Konstantinos K.; Gunter, Marc J.; Kaaks, Rudolf; Schulze, Matthias B.; Turzanski Fortner, Rénee; Antoniussen, Christian S.; Dahm, Christina C.; Mellemkjær, Lene; Tjønneland, Anne; Amiano, Pilar; Ardanaz, Eva; Colorado-Yohar, Sandra M.; Rodriguez-Barranco, Miguel; Tin Tin, Sandar; Agnoli, Claudia; Masala, Giovanna; Panico, Salvatore; Sacerdote, Carlotta; May, Anne M.; Borch, Kristin Benjaminsen; Rylander, Karin Charlotta Maria; Skeie, Guri; Christakoudi, Sofia; Aune, Dagfinn; Weiderpass, Elisabete; Dossus, Laure; Riboli, Elio; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      Evidence linking body fatness to breast cancer (BC) prognosis is limited. While it seems that excess adiposity is associated with poorer BC survival, there is uncertainty over whether weight changes reduce mortality. This study aimed to assess the association between body fatness and weight changes pre- and postdiagnosis and overall mortality and BC-specific mortality among BC survivors. Our study ...
    • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 

      Baumeister, Sebastian E.; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J.; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno-de-Mesquita, Hendrik Bastiaan; Vermeulen, Roel; May, Anne M.; Borch, Kristin Benjaminsen; Oyeyemi, Sunday Oluwafemi; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Chirlaque López, María Dolores; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K.; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-22)
      <i>Background & Aims</i> - To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).<p><p> <i>Methods</i> - We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder ...
    • Association between soft drink consumption and mortality in 10 European countries 

      Mullee, Amy; Romaguera, Dora; Pearson-Stuttard, Jonathan; Viallon, Vivian; Stepien, Magdalena; Freisling, Heinz; Fagherazzi, Guy; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Tjønneland, Anne; Halkjær, Jytte; Overvad, Kim; Weiderpass, Elisabete; Skeie, Guri; Parr, Christine Louise; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Tong, Tammy Y.N.; Schmidt, Julie A.; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Verschuren, W.M. Monique; Boer, Jolanda M.A.; Vermeulen, Roel; Ramne, Stina; Sonestedt, Emily; Van Guelpen, Bethany; Holgersson, Pernilla Lif; Tsilidis, Konstantinos K.; Heath, Alicia K.; Muller, David; Riboli, Elio; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p> <i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p> <i>Design, ...
    • Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study 

      Perrier, Flavie; Viallon, Vivian; Ambatipudi, Srikant; Ghantous, Akram; Cuenin, Cyrille; Hernandez-Vargas, Hector; Chajès, Véronique; Baglietto, Laura; Matejcic, Marco; Moreno-Macías, Hortensia; Kühn, Tilman; Boeing, Heiner; Karakatsani, Anna; Kotanidou, Anastasia; Trichopoulou, Antonia; Sieri, Sabina; Panico, Salvatore; Fasanelli, Francesca; Dollé, Martijn; Onland-Moret, Charlotte; Sluijs, Ivonne; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Huerta, José María; Ardanaz, Eva; Dorronsoro, Miren; Tong, Tammy Y.N.; Tsilidis, Konstantinos K.; Riboli, Elio; Gunter, Mark J.; Herceg, Zdenko; Ferrari, Pietro; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-02)
      <i>Background</i> - There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the association of dietary folate and alcohol intake on leukocyte DNA methylation levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) ...
    • Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Nadal-Zaragoza, Núria; Tjønneland, Anne; Mellemkjær, Lene; Hajji-Louati, Mariem; Truong, Thérèse; Katzke, Verena; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Di Girolamo, Chiara; Skeie, Guri; Borch, Kristin Benjaminsen; Olsen, Karina Standahl; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Guevara, Marcela; Sund, Malin; Bodén, Stina; Gunter, Marc J.; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Aguilera-Buenosvinos, Inmaculada; Tsilidis, Kostas K.; Heath, Alicia K.; Aune, Dagfinn; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
      Background - The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.<p> <p>Methods - A total of 13,270 incident breast ...
    • Association of menopausal characteristics and risk of coronary heart disease: A pan-European case-cohort analysis 

      Dam, Veerle; van der Schouw, Yvonne T.; Onland-Moret, N. Charlotte; Groenwold, Rolf H.H.; Peters, Sanne A.E.; Burgess, Stephen; Wood, Angela M.; Chirlaque, Maria-Dolores; Moons, Karel G.M.; Oliver-Williams, Clare; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Holm, Marianne; Tjønneland, Anne; Kühn, Tilman; Fortner, Renée T.; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Ferrari, Pietro; Gunter, Marc; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Salamanca-Fernández, Elena; Arriola, Larraitz; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Colorado-Yohar, Sandra; Matullo, Giuseppe; Overvad, Kim; Clavel-Chapelon, Francoise; Boeing, Heiner; Ramõn Quirõs, Jose; di Angelantonio, Emanuele; Langenberg, Claudia; Sweeting, Michael J.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      <i>Background</i> - Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these ...
    • Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort 

      Butt, Julia; Jenab, Mazda; Werner, Jill; Fedirko, Veronika; Weiderpass, Elisabete; Dahm, Christina C.; Tjønneland, Anne; Olsen, Anja; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Turzanski-Fortner, Renée; Aleksandrova, Krasimira; Schulze, Matthias B.; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosaria; Sacerdote, Carlotta; Bueno-De-Mesquita, Bas; van Gils, Carla H.; Gram, Inger Torhild; Lukic, Marko; Sala, Núria; Sánchez Pérez, Maria José; Ardanaz, Eva; Chirlaque, Maria-Dolores; Palmquist, Richard; Löwenmark, Thyra; Travis, Ruth C.; Heath, Alicia K.; Cross, Amanda J.; Freisling, Heinz; Zouiouich, Semi; Aglago, Elom; Waterboer, Tim; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-20)
      Experimental evidence has implicated genotoxic <i>Escherichia coli (E. coli)</i> and enterotoxigenic <i>Bacteroides fragilis</i> (ETBF) in the development of colorectal cancer (CRC). However, evidence from epidemiological studies is sparse. We therefore assessed the association of serological markers of <i>E. coli</i> and ETBF exposure with odds of developing CRC in the European Prospective Investigation ...
    • Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status 

      Fedirko, Veronika; Jenab, Mazda; Méplan, Catherine; Jones, Jeb S.; Zhu, Wanzhe; Schomburg, Lutz; Siddiq, Afshan; Hybsier, Sandra; Overvad, Kim; Tjønneland, Anne; Omichessan, Hanane; Perduca, Vittorio; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Aleksandrova, Krasimira; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Agnoli, Claudia; Naccarati, Alessio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Weiderpass, Elisabete; Skeie, Guri; Nøst, Therese Haugdahl; Lujan-Barroso, Leila; Quirós, Jose Ramón; Huerta, José María; Rodríguez-Barranco, Miguel; Barricarte, Aurelio; Gylling, Björn; Harlid, Sophia; Bradbury, Kathryn Erica; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Murphy, Neil; Freisling, Heinz; Tsilidis, Kostas; Aune, Dagfinn; Riboli, Elio; Hesketh, John E.; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-25)
      Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein and Se metabolic pathway genes. <i>Illumina Goldengate</i> assays were designed and resulted in the genotyping of 1040 variants in 154 genes ...
    • Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study 

      Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, Mariá-José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay-Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...
    • Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort 

      Matejcic, Marco; De Batlle, Jordi; Ricci, Cristian; Biessy, Carine; Perrier, Flavie; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Cadeau, Claire; His, Mathilde; Cox, David G.; Boeing, Heiner; Fortner, Renée Turzanski; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulou, Antonia; Benetou, Vassiliki; Tumino, Rosario; Panico, Salvatore; Sieri, Sabina; Palli, Domenico; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Skeie, Guri; Amiano, Pilar; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Quirós, José Ramón; Buckland, Genevieve; van Gils, Carla H.; Peeters, Petra H.; Key, Timothy J.; Riboli, Elio; Gylling, Björn; Zeleniuch-Jacquotte, Anne; Gunter, Mark J.; Romieu, Isabelle; Chajès, Véronique (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
      Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually ...
    • Blood polyphenol concentrations and differentiated thyroid carcinoma in women from the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Zamora-Ros, Raul; Lujan-Barroso, Leila; Achaintre, David; Franceschi, Silvia; Kyrø, Cecilie; Overvad, Kim; Tjønneland, Anne; Truong, Therese; Lecuyer, Lucie; Boutron-Ruault, Marie Christine; Katzke, Verena; Johnson, Theron S.; Schulze, Matthias B; Trichopoulou, Antonia; Peppa, Eleni; La Vechia, Carlo; Masala, Giovanna; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Skeie, Guri; Ramón Quirós, J; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María Dolores; Ardanaz, Eva; Almquist, Martin; Hennings, Joakim; Vermeulen, Roel; Wareham, Nicholas J; Tong, Tammy Y.N.; Aune, Dagfinn; Byrnes, Graham; Weiderpass, Elisabete; Scalbert, Augustin; Rinaldi, Sabina; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)
      <p>Background - Polyphenols are natural compounds with anticarcinogenic properties in cellular and animal models, but epidemiological evidence determining the associations of these compounds with thyroid cancer (TC) is lacking. <p>Objectives - The aim of this study was to evaluate the relations between blood concentrations of 36 polyphenols and TC risk in EPIC (the European Prospective Investigation ...
    • Calcium Intake and Lung Cancer Risk: A Pooled Analysis of 12 Prospective Cohort Studies 

      Takata, Yumie; Yang, Jae Jeong; Yu, Danxia; Smith-Warner, Stephanie A.; Blot, William J.; White, Emily; Robien, Kimberly; Prizment, Anna; Wu, Kana; Sawada, Norie; Lan, Qing; Park, Yikyung; Gao, Yu-Tang; Cai, Qiuyin; Song, Mingyang; Zhang, Xuehong; Pan, Kathy; Agudo, Antonio; Panico, Salvatore; Liao, Linda M.; Tsugane, Shoichiro; Chlebowski, Rowan T.; Nøst, Therese Haugdahl; Schulze, Matthias B.; Johannson, Mattias; Zheng, Wei; Shu, Xiao-Ou (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-11)
      Background - Previous studies on calcium intake and lung cancer risk reported inconsistent associations, possibly due to the differences in intake amounts and contributing sources of calcium and smoking prevalence.<p> <p>Objectives - We investigated the associations of lung cancer risk with intake of calcium from foods and/or supplements and major calcium-rich foods in 12 studies.<p> <p>Methods ...
    • Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans 

      Stepien, Magdalena; Hughes, David J.; Hybsier, Sandra; Bamia, Christina; Tjønneland, Anne; Overvad, Kim; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Orfanos, Phlippos; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Lasheras, Cristina; Bonet Bonet, Catalina; Molina-Portillo, Elena; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Ohlsson, Bodil; Sjöberg, Klas; Werner, Mårten; Shungin, Dmitry; Wareham, Nick; Khaw, Kay-Tee; Travis, Ruth C.; Freisling, Heinz; Cross, Amanda J.; Schomburg, Lutz; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-02)
      Background:<br>Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.<br>Methods:<br>A nested ...
    • Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition 

      Bradbury, Kathryn E.; Appleby, Paul N.; Tipper, Sarah J.; Travis, Ruth C.; Allen, Naomi E.; Kvaskoff, Marina; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Cervenka, Iris; Mahamat-Saleh, Yahya; Bonnet, Fabrice; Kaaks, Rudolf; Fortner, Renée T.; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Stratigos, Alexander J.; Palli, Domenico; Grioni, Sara; Matullo, Giuseppe; Panico, Salvatore; Tumino, Rosario; Peeters, Petra H.; Bueno-de-Mesquita, H. Bas; Ghiasvand, Reza; Veierød, Marit B.; Weiderpass, Elisabete; Bonet, Catalina; Molina, Elena; Huerta, José M.; Larrañaga, Nerea; Barricarte, Aurelio; Merino, Susana; Isaksson, Karolin; Stocks, Tanja; Ljuslinder, Ingrid; Hemmingsson, Oskar; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Rinaldi, Sabina; Tsilidis, Konstantinos K.; Aune, Dagfinn; Riboli, Elio; Key, Timothy J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
      Insulin‐like growth factor‐I (IGF‐I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF‐I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF‐I concentrations ...